KMID : 0379119900180030137
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Korean Journal of Mycology 1990 Volume.18 No. 3 p.137 ~ p.144
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Effects of Alkali Extract of Ganoderma lucidum IY007 on Complement and Reticuloendothelial System
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ÀÌÁØ¿ì/Lee, June Woo
À̱ÇÇà/Á¤ÈÆ/Á¤ÃµÈñ/Lee, Kweon Haeng/Jeong, Hoon/Chung, Chun Hee
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Abstract
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To examine effects on complement and reticuloendothelial system, alkali extract was isolated from cultured mycelium of Ganoderma lucidum IY107. It was shown to strongly activate both classical and alternative pathways of complement as compared with krestin. Activated complement C3, 3rd peak, was observed by crossed immunoelectrophoresis. It was also shown to activate reticuloendotherial system of ICR mice in the carbon clearance teat and to increase hemolytic plaque forming cells of the spleen. Carbohydrate and protein contents of the alkali extract were 10% and 49%, respectively. The carbohydrate consisted of four monosaccharides and the protein contained 16 amino acids.
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